The Blind Boys of Alabama are a gospel group from Alabama that first formed at the Alabama Institute for the Negro Blind in 1939. The three main vocalists of the group and their drummer/percussionist are all blind. As of 2008, they continue to tour nationally and internationally, led by the soulful Jimmy Lee Carter singing lead vocals. Mr. Carter is one of the original members from the Alabama Institute for Negro Blind and the Happyland Jubilee Singers (the precursor to the Blind Boys of Alabama). In 2006, Clarence Fountain, the group's former long-time lead vocalist and founding member limited his touring for health reasons. A third founding member, George Scott, died on March 9, 2005 at the age of 75.

Releases by the group in recent years have been favorites at the Grammy Awards—they won the Grammy Award for Best Traditional Soul Gospel Album every year between 2002 to 2005. The Blind Boys of Alabama were inducted into the Gospel Music Hall of Fame in 2007.

Their rendition of Tom Waits' "Way Down in the Hole" was used as the theme song of the HBO series The Wire in its first season.

Their cover of Ben Harper's "I Shall Not Walk Alone" was featured in the first season of ABC's Lost, in the episode "Confidence Man".

The Blind Boys were featured on the Imus in the Morning radio and TV show on November 30, 2006, on The Tonight Show with Jay Leno on December 20, 2006 and March 11, 2008, and on Late Night With Conan O'Brien on February 1, 2008. They have collaborated with numerous artists, including Ben Harper, Aaron Neville and Mavis Staples. They have joined Tom Petty and Peter Gabriel on tour, and will tour with Taj Mahal in 2008. In a surprise to both the band and the audience, the Blind Boys were joined by Prince on stage in a March 7th, 2008 show at the Knitting Factory in Hollywood, California.