Charles Quinton "Charlie" Murphy (born July 12, 1959) is an American writer, actor, and stand-up comedian known for his role on the American television program Chappelle's Show.

Murphy achieved fame as a recurring performer on Chappelle's Show, particularly in the Charlie Murphy's True Hollywood Stories sketches. In these, Murphy recounts his misadventures as part of his brother Eddie's entourage, including encounters with various celebrities such as Rick James and Prince.

After Chappelle's Show host Dave Chappelle left the show, Murphy and Donnell Rawlings hosted the "lost episodes" compiled from sketches produced before Chappelle's departure. In a radio interview, Charlie Murphy has stated that he will be starring in a new Comedy Central reality show with Rawlings. Murphy has done voiceovers for Budweiser radio commercials, Cartoon Network's Adult Swim series The Boondocks and voiced a pimp named Jizzy-B in Rockstar Games' Grand Theft Auto: San Andreas video game. Recently, Murphy provided the voice for Spock on the G4TV's Star Trek 2.0 shorts, and the dog in his younger brother Eddie's 2007 film, Norbit.