The Bank of America 500 is a NASCAR Sprint Cup Series race that is hosted annually at Lowe's Motor Speedway in Concord, North Carolina, United States. The race is usually held in the month of October, and is 500 miles long. Prior to 1966, the race was a 400-mile event.

The day that the race is held was changed following the 2002 running. Due to good ratings in primetime during the event (resulting in part from a three-hour rain delay before the race), track officials moved the 2003 race from Sunday afternoon to Saturday night, where it has been ever since. In 2005, the start was delayed by the finish to the Notre Dame-Southern California college football game which ran late. While the game was in its final minutes, NBC, the broadcaster of both events, had the race engines start and the pace laps proceed. As the pace car pulled off the track to pit road to start the race, NBC had just switched coverage from the game to the race, and the broadcast began as the field took the green flag.