The Pepsi 500 is a NASCAR Sprint Cup Series stock car race held annually at the Auto Club Speedway in Fontana, California. It is the second of two Sprint Cup Series races held at the Auto Club Speedway, the other being the Auto Club 500.

The event was first held in 2004, added as part of the NASCAR Realignment, and many race fans have not embraced its introduction. Since its inception, it has been held as a night race on the Sunday of Labor Day weekend, which was previously the traditional date of the Southern 500 at Darlington. The 2005 race was famous for Kyle Busch becoming the youngest NASCAR Nextel Cup winner ever.

The Pepsi 500 name will first be used in August 2008, with Pepsi taking title sponsorship from Sharp. This announcement was made via the California Speedway website, Pepsi has been the official soft drink sponsor of the speedway since 1997, despite Coca Cola's deal with most other ISC tracks, which began in 2008 and is being phased in over a multi-year period.

Parts of the film Herbie: Fully Loaded were filmed during the 2004 race.